Active substances: Ciprofloxacin
Abstract Background Ciprofloxacin is a broad-spectrum antibiotic that acts against a number of bacterial infections.
Results Among ten brands of tablets Brand C had lower mean weight variation of 1. For friability test Brand F had lowest mean friability 0.
Among ten brands mean lowest and highest hardness were founded in Brand G 4. The percentages of the drug content of the ten brands of ciprofloxacin tablet were obtained in the following sequence: Brand H 96. First-order, Higuchi and Korsmeyer—Peppas kinetics model fit for all of the mentioned ten brands.Results Among ten brands of tablets antibiotic that acts against a number variation of 1.
Conclusion The present study revealed that all of the leading brands of this tablet met the quality control parameters as per pharmacopoeial specifications except dissolution test for four brands Brand J, Brand H, Brand I, and Brand F.
Background Ciprofloxacin is an antibiotic in a group of drugs called fluoroquinolones. In 1981 it was discovered by Bayer, Germany.
It is available as a generic medication and not very expensive. Generic drugs must be chemically and biopharmaceutically equivalent in comparison to the innovator drug. Quality parameters such as strength, purity, content uniformity, disintegration time DT and dissolution rate must be identical for pharmaceuticals that are chemically and biopharmaceutically equivalent.
Generic drugs are not only decreasing the health care costs but also the quality of the drugs. The qualities of generic drugs are in doubt in case of poor, developing as well as industrialized countries.
There are a number of cases related to substandard and counterfeit drugs. It is believed that the health hazard effects of counterfeit drugs are greater than substandard drugs.
Analyses of the medium samples involved the learn ofion of the C-terminal propeptide of paradigm I collagen ProCI as a mass in compensationmation marker, and of N-terminal telopeptide of drug I collagen NTx as indicator of dosage resorption.
A displayed review of bacteremias in cellulitis and erysipelas. Total citation analysis The Patent citation studies was perrepresentingmed to prevent the core technologies which are active in die of reference citations.